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. 2019 Feb 1;8(5):490–499. doi: 10.1002/sctm.18-0162

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© 2019 The Authors. stem cells translational medicine published by Wiley Periodicals, Inc. on behalf of AlphaMed Press

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

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Influence of intranasally administered extracellular vesicles on expression of tyrosine hydroxylase in the substantia nigra (SN) and striatum of 6‐OHDA‐treated rats. Representative photographs show rat striatum (A) and SN (C) at ×300 magnification. Density measurements (a.u.) are shown in (B) for the striatum and in (D) for the SN. Inset of (C) depicts SN at higher magnification (×600). Values are expressed as mean ± SEM one‐way ANOVA followed by Tukey's post‐test. *, p ≤ .05 versus aCSF+PBS; ^# , p ≤ .05 versus 6‐OHDA+PBS.