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. 2019 Apr 16;10:309. doi: 10.3389/fphys.2019.00309

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Copyright © 2019 Watson, Gould, Penfold, Lambert, Pratama, Dai, Gray, Head and Jandeleit-Dahm.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Mean arterial pressure (MAP; A,B), systolic BP (sBP; C,D), and diastolic BP (dBP; E,F), 24 h recordings were taken from conscious mice implanted with telemetric blood pressure probes after 10 weeks of study (24 h averages: B,D,F). Diabetic hypertensive mice maintained a high blood pressure despite polyuria and polydipsia. n = 3–9/group. Mean ± SEM. 2-factor ANOVA p-values: I, interaction; D, relative to diabetic status; S, relative to strain. t-test p < 0.05: ^∗ vs Cont. Normot.; ‡ vs Diab. Normot.