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. 2019 Apr 16;9:271. doi: 10.3389/fonc.2019.00271

Table 2.

The relation between clinicopathological parameters and pre-treatment red cell distribution width levels of patients with laryngeal squamous cell cancer.

RDW quartiles
≤12.9% (n = 242) 12.9 −13.2% (n = 244) 13.2–13.5% (n = 179) >13.5% (n = 144) Chi-Square/t value P-Value for Trend
Age (years) 60.42 60.89 60.60 60.58 0.094 0.963
40–89 31–84 30–89 27–85
Death events 25 37 60 64 45.333 < 0.001
Duration of follow-up 78.84 73.87 69.81 64.84 7.393 < 0.001
6–115 3–115 12–114 7–116
Smoking 178 174 121 92 0.826 0.363
Drinking 98 81 69 59 0.026 0.871
Hypertension 64 75 50 37 0.025 0.875
RBC 4.35 4.33 4.22 4.22 2.173 0.038
Hg 137.50 132.15 131.31 131.27 10.173 < 0.001
Radiotherapy 32 35 38 35 7.134 0.008
Chemotherapy 5 7 10 6 2.535 0.111
T STAGE
T1 37 77 40 41 3.434 0.064
T2 163 37 50 75 4.891 0.027
T3 24 126 79 8 0.084 0.772
T4 18 4 10 20 4.648 0.031
N STAGE
N0 242 214 130 132 1.420 0.233
N1 0 20 3 8
N2−3 0 10 46 4
TNM STAGE
I 37 77 40 41 3.434 0.064
II 163 27 39 71 8.069 0.005
III 24 129 53 8 0.769 0.380
IV 18 11 47 24 18.486 < 0.001
HISTOLOGICAL DIFFERENTIATION
Highly or moderately differentiated 207 199 149 115 0.145 0.703
Poorly differentiated 5 5 11 1 0.137 0.712
OPERATION THERAPY
Total laryngectomy 66 109 97 54 4.599 0.032
Partial laryngectomy 176 135 82 90 8.569 0.036

RDW, red cell distribution width; Hg, hemoglobin; WBC, white blood cell; RBC, red blood cell count; BMI, body mass index.