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. 2019 Apr 16;10:430. doi: 10.3389/fphys.2019.00430

Table 1A.

Changes in body weight and body composition during moderate altitude.

Authors Participants
M/F, Age [years]
Type of exposure
Diet manipulation
Altitude level
[m]
Duration
[days]
Body weight
[Δkg (Δ% of BW)]
Body composition
[Δkg (Δ%)]
Passive Active Yes/No FFM FM MM TBW
Moderate altitude
Ocobock (2017) 18-31 yrs
G1(temperate): 37 M
G2(cold): 22 M
G3(temperate): 16 F
G4 (cold): 6 F
Endurance
Temperate
Cold
Temperate
Cold
No
(recordings)
3205-3658 84; G1:
112; G2:
84; G3:
112; G4:
–2.8 (–3.6)
–2.3 (–3.0)
–1.1 (–1.6)
–2.1 (–3.0)
–1.9 (–21.0)
–0.8 (–9.6)
–1.6 (–9.5)
–2.6 (–14.6)
–0.9 (–1.4)
–1.5 (–2.3)
0.5 (1.0) ns
0.6 (+1.2)
Jacobs et al. (2016) 8 M, 1 F
26.9 ± 3.7 yrs
Sea level activity No 3454 28
Mekjavic et al. (2016) 11 M
23.7 ± 4.0 yrs
Stay at simulated altitude No
(recordings,
ad libitum)

2800
3000
3200
3400
(10)
2
2
3
3
–0.9 (–1.2) ns –0.8 (–1.3) ns –0.1 (–0.9) ns
Kasprzak et al. (2015) 9 M
28.0 ± 4.3 yrs
Ascents No
(dietary recordings, ad libitum)
3200 up to 3800 14 –1.6 (–2.2) –1.1 (–1.9) ns –0.5 (–4.0) ns –0.7 (–1.5) ns
Chia et al. (2013) 10 M
14.9 ± 0.4 yrs
Daily Swimming No 2300 21 0.1 (0.1) ns 0.8 (+1.5) –1.7 (–11.4)
Chen et al. (2010) 12 M
31 ± 1.1 yrs
Daily hiking No
(ad libitum)
between 2200 and 3800 25 –1.4 (–2.0) ns –2.1 (–15.3)
Lippl et al. (2010) 20 M
55.7 ± 4 yrs
Stay at natural altitude No
(no diet restrictions)
2650 7 –1.5 (–1.4) na (–0.3) ns na (0.1) ns
Greie et al. (2006) 36 M
56 yrs (36-66 yrs)
12 hiking sessions No
(standardized nutrition menues, no dietary restrictions)
1700+ 21 –3.3 (∼-3.3)
Gunga et al. (2003) 22 M
54 yrs (40-64 yrs)
Hiking and swimming No
(ad libitum)
∼1700 21 –0.4 (–0.4) 1.6 (2.4) ns 0.6 (1.2)
Tanner and Stager (1998) 5 M
40.0 ± 5.5 yrs
Trekking No
(Dietary recordings, no attempt to manipulate diet, goal: 5500 kcal/day)
2200-4300 21 –4.2 (–5.4) –3.1 (–4.7) –1.0 (–8.2)
Hoyt et al. (1994) 6 M
31 ± 4 yrs
Strenuous winter exercise Yes
(prescribed diet, US military field ration (22.7 MJ/d) dietary records)
2500-3100 5 –1.8 (–2.3) –0.4 (–0.6) ns –1.4 (na) –0.1 (–0.2) ns
Schena et al. (1992) 11 M, 5 F
35.8 ± 5.6 yrs
G1: dietary supplementation
G2 placebo
Trekking Yes
(dietary recordings, amino acid supplementation)
2500-4000
(4 d < 3000)
21; G1
21; G2
–1.0 (–1.6)
–1.8 (–2.8)
0.7 (1.5) ns
–0.2 (–0.4) ns
–1.8 (–11.8)
–1.6 (–10.2)
Greenleaf et al. (1978) 6 M
21-23 yrs
G1: n = 3
G2: n = 3
Running (2 × 30 min/day) simulated altitude Yes
controlled diet (3309 kcal/day)G1 with fluid replacement
G2 drank ad libitum
2287 8 –0.6 (–0.9)

Studies presented in square brackets are not included in the meta-analysis due to missing data. M, male; F, female; yrs, years (mean ± SD or min-max) d, days; ns, non-significant; n.a., no data available; Δkg, mean changes in BW, FFM, FM, MM and TBW before and after data collection or mean changes over a defined period; Δ%, mean change in percent compared to baseline or to a defined period; BW, bodyweight; FFM, fat free mass; FM, fat mass; MM, muscle mass; TBW, total body water; G, study groups. If no data were available but direction of change was illustrated, arrow is indicated: ↔ no change.