Table 3.
Molecular MIC analysis of Y. pestis strains.
| Normalized FCa |
||||
|---|---|---|---|---|
| Doxycycline (μg/ml) | Kim53b | EV76b | KIM D27b | A1122b |
| 0.125 | 33 ± 10 | 30 ± 6.3 | 6.1 ± 4.0 | 18 ± 5.0 |
| 0.25 | 160 ± 93 | 130 ± 21 | 45 ± 25 | 42 ± 4.8 |
| 0.5 | 503 ± 355c | 433 ± 86c | 173 ± 94c | 152 ± 13 |
| 1 | 240 ± 170 | 296 ± 65 | 126 ± 78 | 257 ± 116c |
| 2 | 46 ± 30 | 128 ± 173 | −8.3 ± 14 | 0.7 ± 53 |
| 4 | 105 ± 119 | −20 ± 54 | −6.5 ± 11 | 34 ± 55 |
aThe presented results are the average and standard deviation of three independent experiments. bThe standard doxycycline MIC of the strains is 0.25–1 μg/ml. cThe mMIC of the strains is indicated in bold.