Discrete variables	Category of recruitment								Total		P-value*
	ME/CFSsa		ME/CFSmm		MS		HC
	(n)	(%)	(n)	(%)	(n)	(%)	(n)	(%)	(n)	(%)
SEX
Male	13	24.1	47	24.0	10	20.4	28	26.2	98	24.1	0.89
Female	41	75.9	149	76.0	39	79.6	79	73.8	308	75.9
IMMUNE-RELATED SYMPTOMS
No symptoms	0	0.0	10	5.1	25	51.0	74	69.1	109	26.9	0.000
Some symptoms	22	40.7	83	42.6	20	40.8	31	29.0	156	38.5
Moderate/severe symptoms	32	59.3	102	52.3	4	8.2	2	1.9	140	34.6
VIRAL SEROLOGY RESULTS
CMV positive	18	33.3	57	29.4	18	45.0	40	37.4	133	33.8	0.40
EBV combined positive	48	88.9	171	88.1	39	95.5	99	93.4	357	90.6	0.42
HSV1 positive	29	53.7	82	42.3	23	57.5	45	42.4	179	45.4	0.49
HSV2 positive	22	40.7	76	39.2	16	40.0	36	33.9	150	38.1	0.12
VZV positive	52	96.3	190	97.9	39	97.5	104	98.1	385	97.7	0.85
HHV6 positive	52	96.3	177	91.2	36	90.0	102	96.2	367	93.1	0.48