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. 2019 Apr 16;10:811. doi: 10.3389/fmicb.2019.00811

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Copyright © 2019 Vielle, García-Nicolás, Oliveira Esteves, Brügger, Summerfield and Alves.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Gene expression levels of antiviral mediators and pro-inflammatory cytokines by NECs after flavivirus infection. IFN-β (A) IFN-λ1 (B), IFN-λ2/3 (C), IL-6 (D), IL-8/CXCL8 (E), and IP-10/CXCL10 (F) mRNA levels measured by quantitative RT-PCR. Each symbol represents an independent donor (donor I: dot, donor II: square, donor III: upward triangle, donor IV: diamond, donor V: circle, and donor VI: downward triangle). Data are presented as mean and SD and stars indicate significance levels. *p < 0.05; **p < 0.01; ***p < 0.001.