Table 4.
Agreement between 2 pathologists for the assessment of necrosis, histology, Ki-67, and mitotic count on primary tumour and metastasis.
| Primary tumours |
Metastases |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Second pathologist | Second pathologist | |||||||||
| Histology | TC | AC | TC | AC | ||||||
| First pathologist | TC | 3 | 0 | Kappa (95% CI) | TC | 7 | 0 | Kappa (95% CI) | ||
| AC | 4 | 7 | 0.43 (0.04-0.82) | AC | 3 | 9 | 0.69 (0.38-0.99) | |||
| Necrosis | No | Yes | No | Yes | ||||||
| First pathologist | No | 4 | 0 | Kappa (95% CI) | No | 9 | 0 | Kappa (95% CI) | ||
| Yes | 7 | 3 | 0.20 (0.00-0.45) | Yes | 6 | 4 | 0.39 (0.07-0.71) | |||
| Mitoses | 0-1 | 2-4 | 5-9 | 0-1 | 2-4 | 5-9 | ||||
| First pathologist | 0-1 | 5 | 0 | 0 | Kappa (95% CI) | 0-1 | 8 | 0 | 1 | Kappa (95% CI) |
| 2-4 | 2 | 5 | 0 | 0.65 (0.31-0.98) | 2-4 | 3 | 5 | 1 | 0.45 (0.13-0.76) | |
| 5-9 | 1 | 0 | 1 | 5-9 | 0 | 1 | 0 | |||
| Ki-67 LI | 0-1 | 2-4 | 5-9 | 0-1 | 2-4 | 5-9 | ||||
| First pathologist | 0-4 | 2 | 0 | 0 | Kappa (95% CI) | 0-4 | 2 | 0 | 0 | Kappa (95% CI) |
| 5-9 | 3 | 5 | 0 | 0.56 (0.20-0.91) | 5-9 | 3 | 5 | 0 | 0.75 (0.52-0.98) | |
| 10+ | 0 | 1 | 3 | 10+ | 0 | 0 | 9 | |||
Abbreviations: AC, atypical carcinoid; CI, confidence interval; TC, typical carcinoid.