Table 3.
The MDA content and activities of SOD and GSH-Px in the brains of mice following 12 weeks of exposure to fluoride
| Group | n | MDA (nmol/mg pr) |
SOD (U/mg pr) |
GSH-Px (kU/l) |
|---|---|---|---|---|
| WT | 10 | 2.36 ± 0.12 | 206.85 ± 15.97 | 334.88 ± 5.53 |
| WT+LF | 10 | 2.60 ± 0.19 | 185.16 ± 16.01* | 314.15 ± 12.5* |
| WT+HF | 10 | 5.36 ± 0.29*# | 101.32 ± 12.41*# | 139.54 ± 11.28*# |
| APP/PS1 | 10 | 4.77 ± 0.13* | 124.14 ± 7.71* | 189.91 ± 5.43* |
| APP/PS1+LF | 10 | 6.79 ± 0.43*^ | 81.55 ± 4.43*^ | 126.05 ± 8.87*^ |
| APP/PS1+HF | 10 | 7.47 ± 0.33*^& | 62.82 ± 11.63*^& | 79.92 ± 18.61*^& |
Notice: WT, wild-type; LF, low fluoride; HF, high fluoride; APP/PS1, amyloid precursor protein/presenilin 1; pr, protein. The values presented are *P < 0.05 vs control (WT); #P < 0.05 vs LF; ^P < 0.05 vs APP/PS1; &P < 0.05 vs APP/PS1+LF, as determined by analysis of variance (ANOVA), followed by the least significant differences post hoc test