Table 5.

Parameters in APP metabolism and synaptic proteins between genders of mice in different groups

	APP/PS1		APP/PS1+LF		APP/PS1+HF
	Male	Female	Male	Female	Male	Female
BACE1	0.51 ± 0.20	0.49 ± 0.40	0.70 ± 0.30	0.62 ± 0.25	0.77 ± 0.20	0.80 ± 0.75
ADAM10	0.53 ± 0.20	0.47 ± 0.10	0.24 ± 0.10	0.36 ± 0.15	0.30 ± 0.20	0.23 ± 0.25
BACE2	0.43 ± 1.10	0.57 ± 0.75	0.44 ± 1.20	0.54 ± 0.90	0.37 ± 0.35	0.46 ± 0.50
SNAP-25	0.43 ± 0.10	0.57 ± 0.10	0.50 ± 0.95	0.41 ± 0.15	0.28 ± 0.30	0.37 ± 0.25
SYP	0.54 ± 0.15	0.46 ± 0.15	0.36 ± 0.10	0.46 ± 0.10	0.33 ± 0.05	0.29 ± 0.10

Notice: APP/PS1, amyloid precursor protein/presenilin 1; LF, lower fluoride; HF, high fluoride. The values shown are means ± SD (n = 5) as determined by analysis of variance (ANOVA), followed by the least significant differences post hoc test