Furian 2018.
Methods | Double‐blind randomized, placebo‐controlled trial |
Participants | 118 people with COPD were studied in Bishkek (760 m), Kyrgyz Republic; and after travelling within 6 hours to Tuja Ashu clinic (3200 m) stayed there for 3 days. |
Interventions | Participants received dexamethasone (2 × 4 mg/d) or placebo before ascent and during stay at 3200 m |
Outcomes | Cumulative risk of 1 of the following: AMS (AMS environmental symptom cerebral score ≥ 0.7); severe hypoxaemia (SpO₂ < 75% for > 30 min); or discomfort requiring descent to low altitude |
Notes | Related to systematic review Nieto 2017 |