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. 2019 Apr 23;2019(4):CD013315. doi: 10.1002/14651858.CD013315

NCT01993667.

Trial name or title Acetazolamide for the prevention of high altitude illness: a comparison of dosing
Methods Interventional
Participants Inclusion criteria
  1. 18 years or older

  2. English or Indian speaking

  3. Mountaineers or trekkers who plan to climb Mt. McKinley or trek to Base Camp on Mt. Everest


Exclusion criteria
  1. Low sodium and/or potassium blood serum levels

  2. Kidney disease or dysfunction

  3. Liver disease, dysfunction, or cirrhosis

  4. Suprarenal gland failure or dysfunction

  5. Hyperchloraemic acidoses

  6. Angle‐closure glaucoma

  7. Taking high dose aspirin (over 325 mg/day)

  8. Any reaction to sulfa drugs or acetazolamide

  9. Pregnant or lactating women

Interventions Drug: acetazolamide
Outcomes
  1. Prevention of acute mountain sickness as measured by the Lake Louise Score (time frame: 1 year)

  2. Side effect profile of acetazolamide (time frame: 1 year)

Starting date March 2012
Contact information Scott McIntosh, MD
Notes Recruiting