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. 2019 Feb 7;68(5):1062–1072. doi: 10.2337/db18-0883

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© 2019 by the American Diabetes Association.

Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered. More information is available at http://www.diabetesjournals.org/content/license.

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Comparison between human and mouse jejunum peptidome. Tissue samples were analyzed by nano-LC-MS/MS and compared between human jejunum (n = 4) and mouse mid–small intestine (n = 4). Peptides were assigned to their parental proteins by Peaks software, and protein intensity was calculated by Peaks v8.0 for all proteins detected corresponding to genes with 1:1 homology between human and mouse for jejunum mucosal homogenates. A: All proteins. B: Proteins from genes enriched in at least one of the species from the human and the mouse transcriptome data sets. Enrichment was defined as adjusted P ≤ 0.1, fold difference >4, and base mean expression >50 from DESEQ2 model. Colors indicate in which species the mRNA for the genes was enriched.