Table 3.
lncRNAs regulating human adipocyte biology
| lncRNA | Role in human adipocyte differentiation and function | Proposed mechanism of action | Ref. |
|---|---|---|---|
| HOTAIR | Positive | Unknown | (101) |
| ADINR | Positive | Binds to PA1 and recruits MLL3/4 to regulate chromatin architecture | (79) |
| linc-NFE2L3–1 | Negative | Unknown | (102) |
| H19 | Negative | Targets miR-675 and HDACs 4–6 | (64) |
| MIR31HG | Positive | Unknown | (103) |
| ASMER-1 ASMER-2 | Positive | Unknown | (80) |
| HOXA11-AS1 | Positive | Unknown | (104) |
| linc-ADAL | Positive | Interacts with hnRNPU and IGF2BP2 at distinct subcellular locations | (35) |
| RP11–20G13.3 | Positive | Unknown | (105) |
| MEG3 | Negative | Regulates miR-140-5p | (106) |