Skip to main content
. 2019 Feb 14;68(5):932–938. doi: 10.2337/db18-0981

Figure 1.

Figure 1

Platelet counts, circulating half-life, and regeneration in diabetic mice. A: Blood glucose concentrations were measured at the indicated times after STZ or citrate buffer administration (n > 6) in wild-type mice (control), diabetic wild-type mice (control-STZ), nondiabetic platelet GLUT1/3 DKO mice (DKO), and diabetic DKO mice (DKO-STZ). B: Platelet counts in whole blood (n = 10). C: Platelet circulating half-life was determined after administration of GPIbβ antibodies (n = 6). D: Platelet regeneration was determined by monitoring platelets counts after depletion of platelets following administration of GPIbα antibodies (black arrow) (n = 6). Error bars are SD. ****P < 0.0001 relative to control genotype. B: One-way ANOVA followed by Tukey post hoc test. A, C, and D: Two-way ANOVA followed by Bonferroni multiple comparison post hoc test.