Fig. 5.

GO term prediction for 20 proteins in the Map Kinase signaling pathway. iGFP was run six iterations and the F-score was reported at each iteration (Iter1–Iter 5 and IterLast). iGFP results were compared with GO assignment with a GO enrichment analysis (ENRICH). Two tests were performed: prediction after removing a fraction of GO terms (panel A, C, E) and after removing all GO annotations from a fraction of target proteins (panel B, D, F). A, F-score of the GO term removal test; B, F-score of the protein removal test; C, recall of the GO term removal test; D, recall of the protein removal test; E, precision of the GO term removal test; F, precision of the protein removal test