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. 2018 Sep 19;35(8):1373–1379. doi: 10.1093/bioinformatics/bty810

Table 1.

The estimated type I error rates divided by the nominal significance level of CLC for 20, 40 and 100 quantitative phenotypes under four models

K Sample Alpha Model 1 Model 2 Model 3 Model 4
20 1000 0.01 1.02 0.84 0.85 0.96
0.001 0.80 0.80 0.70 1.10
2000 0.01 1.03 0.93 0.96 0.94
0.001 0.90 0.80 1.20 1.10
40 1000 0.01 1.08 0.82 1.00 1.02
0.001 1.20 0.70 1.40 1.30
2000 0.01 0.91 0.91 1.03 0.94
0.001 1.10 1.50 1.50 0.50
100 1000 0.01 0.95 1.03 0.82 0.89
0.001 0.65 1.05 0.65 0.95

Note: The P-values of CLC are evaluated by 10 000 simulations and type I error rates are evaluated by 10 000 replicated samples.