Table 2.
The association [multivariable odds ratio (OR)1] between dietary folate, supplemental and total folate intake with depression for all races and the three race/ethnic groups.
| All Races (N = 3687) | Non-Hispanic white (N=1,928) | Hispanic (N = 959) | African American (N=638) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Folate Variable: | OR | (95% CI) | p-value | OR | (95% CI) | p-value | OR | (95% CI) | p-value | OR | (95% CI) | p-value |
| Diet (residual quartile) | ||||||||||||
| 1st | 1.00 | -- | -- | 1.00 | -- | -- | 1.00 | -- | -- | 1,00 | -- | -- |
| 2nd | 0.91 | (0.53, 1.54) | 0.70 | 1.15 | (0.46, 2.90) | 0.75 | 0.87 | (0.32,2,31) | 0,76 | 0,73 | (0.32, 1.67) | 0.44 |
| 3rd | 0.84 | (0.56, 1.27) | 0.39 | 1.04 | (0.56,1,92) | 0.89 | 0.64 | (0.21, 1,97) | 0,42 | 0,42 | (0.17, 1.04) | 0.06 |
| 4th | 0.95 | (0.59, 1.54) | 0.83 | 1.48 | (0.69, 3.18) | 0.29 | 0.25 | (0.09, 0,70) | 0,01 | 0,87 | (0.48, 1.58) | 0.63 |
|
p trend Supplement |
0.79 | 0.17 | 0.02 | 0.24 | ||||||||
| 1st | 1.00 | -- | -- | 1.00 | -- | -- | 1.00 | -- | -- | 1,00 | -- | -- |
| 2nd | 0.90 | (.53, 1.54) | 0.74 | 0.69 | (0.49, 1.48) | 0.54 | 1.39 | (0.52, 3,73) | 0,49 | 0.69 | (0.23,2.13) | 0.50 |
| 3rd | 0.69 | (0.36, 1.29) | 0.28 | 0.22 | (0.26, 1.52) | 0.28 | 1.00 | (0.20, 5,09) | 0,99 | 0,49 | (0.14, 1.71) | 0.24 |
|
p trend Diet + Supplement (residual quartile) 1st |
0.24 | 0.23 | 0,76 | 0.32 | ||||||||
| 2nd | 0.67 | (0.44, 1.03) | 0.06 | 0.63 | (0.32, 1.24) | 0.17 | 0.69 | (0.23,2,04) | 0,48 | 0,60 | (0.30, 1.20) | 0.14 |
| 3rd | 0.77 | (0.47, 1.27) | 0.28 | 0.99 | (0.48, 2.04) | 0.97 | 0.26 | (0.09, 0,74) | 0.02 | 0,82 | (0.42, 1.59) | 0.53 |
| 4th | 0.73 | (0.44, 1.22) | 0.22 | 0.84 | (0.40, 1.77) | 0.63 | 0.63 | (0.21, 1.95) | 0,40 | 0,46 | (0.15, 1.41) | 0.16 |
| p trend | 0.37 | 0.92 | 0.19 | 0.14 | ||||||||
1
Covariatcs include: use of anti-depressants in past month. SES (income-to-poverty ratio), physical activity, smoking status, dietary B6 and race/ethnicity (only for all races combined). P-value for interaction with race/ethnicity = 0.03 for diet, 0.67 for supplement, and 0.46 for diet + supplement.