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. 2017 Apr 21;2017(4):CD011384. doi: 10.1002/14651858.CD011384.pub2

Ebbehøj 1985.

Methods Randomised clinical trial
Participants Country: Denmark
 Number randomised: 30
 Postrandomisation dropouts: 0 (0%)
 Revised sample size: 30
 Average age: 55 years
 Women: 10 (33.3%)
 Acute interstitial oedematous pancreatitis: not stated
 Necrotising pancreatitis: not stated
 Mild pancreatitis: not stated
 Moderate pancreatitis: not stated
 Severe pancreatitis: not stated
 Persistent organ failure: not stated
 Infected pancreatitis: not stated
 Inclusion criteria: people with acute pancreatitis
Interventions Group 1: NSAID (n = 14), indomethacin 50 mg PR twice daily for 7 days
 Group 2: placebo (n = 16)
Outcomes Hospital stay
Follow‐up: not stated (probably until discharge)
Notes
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Comment: this information was not available.
Allocation concealment (selection bias) Unclear risk Comment: this information was not available.
Blinding of participants and personnel (performance bias) 
 All outcomes Low risk Quote: "[c]ontrolled double‐blind trial".
Blinding of outcome assessment (detection bias) 
 All outcomes Low risk Quote: "[c]ontrolled double‐blind trial".
Incomplete outcome data (attrition bias) 
 All outcomes Low risk Comment: there were no postrandomisation dropouts.
Selective reporting (reporting bias) High risk Comment: either mortality or adverse events were not reported.
For profit‐bias High risk Quote: "[i]ndomethacin (Confortid) and placebo were generously supplied by Dumex Ltd, Denmark".
Other bias Low risk Comment: no other risk of bias