Fig. 1.

Effects of lithium (Li) treatment on acquisition and memory performance in the water maze. All rats improved their ability to find the hidden platform as showed by decreasing escape latency (A) and distance moved (B) over training days. Swimming speed (C) did change as a function of day and was affected by Li treatment. Li-treated rats (n=19) spent less time in target quadrant than control rats (n=22) (D). Data are expressed as mean±standard error of mean. *vs. control rats. Note that Li-treated rats performed spatial learning task as control rats however underperformed retrieval task.