Skip to main content
. 2017 Apr 26;2017(4):CD010770. doi: 10.1002/14651858.CD010770.pub2

Prasad 2013.

Methods Single‐centre placebo RCT
Participants Participants randomised to 1 of 2 groups (n = 62)
‐ Mifepristone 10 mg
‐ Placebo
Inclusion criteria
‐ Symptomatic fibroids
No additional details available
Setting: Delhi, India
Interventions Mifepristone 10 mg orally daily vs placebo
Duration: 3 months
Outcomes Outcomes assessed at baseline and at 3 months
Primary outcome
‐ Fibroid volume
Secondary outcomes
‐ Endometrial biopsy. Reported on 'cystic glandular hyperplasia' but pathology criteria not available
‐ Hormone profile
‐ Fibroid symptoms
‣ Bleeding/amenorrhoea
‣ Dysmenorrhoea
Notes  
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk "Randomized" ‐ no details. Attempts to contact study authors unsuccessful
Allocation concealment (selection bias) Unclear risk Not stated. Attempts to contact study authors unsuccessful
Blinding of participants and personnel (performance bias) 
 All outcomes Unclear risk "Single blind" ‐ no further details. Attempts to contact study authors unsuccessful
Blinding of outcome assessment (detection bias) 
 All outcomes Unclear risk "Single blind" ‐ no further details. Attempts to contact study authors unsuccessful
Incomplete outcome data (attrition bias) 
 All outcomes Unclear risk No details. Attempts to contact study authors unsuccessful
Selective reporting (reporting bias) Unclear risk No details. Attempts to contact study authors unsuccessful
Other bias Unclear risk Data in form of conference proceedings. No published follow‐up data. Protocol not found on clinicaltrials.gov