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| Methods | Parallel randomized controlled trial |
| Participants | Patients diagnosed with rheumatic valve diseases undergoing heart valve replacement operations |
| Interventions | Telmisartan, captopril, and placebo |
| Outcomes | Pulmonary vascular resistance, A‐aDO2, pulmonary neutrophil count, SOD malondialdehyde, NO, angiotensin II; Complications and hospital time. |
| Notes |
