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. 2019 Apr 23;2019(4):CD009537. doi: 10.1002/14651858.CD009537.pub3

Summary of findings for the main comparison. Single‐component hydration intervention versus control for preventing delirium in older people in institutional long‐term care.

Single‐component hydration intervention versus control for preventing delirium in older people in institutional long‐term care
Patient or population: people at risk of delirium in institutional long‐term care
 Settings: long‐term care institutions
 Intervention: single‐component hydration intervention
 Comparison: control
Outcomes Anticipated absolute effects* (95% CI) Relative effect
 (95% CI) No of participants
 (studies) Certainty of the evidence
 (GRADE) Comments
Risk with control Risk with single‐component hydration intervention versus control
Prevalence of delirium
Not measured
Incidence of delirium
NEECHAM Confusion Scale
Follow‐up: mean 4 weeks
Study population RR 0.85 
 (0.18 to 4.0) 98
 (1 study) ⊕⊝⊝⊝
 Very lowa,b,c  
67 per 1000 57 per 1000
 (12 to 268)
Severity of delirium Not measured
Mortality Not measured
Cognitive function Not measured
Falls Not measured
Hospital admissions Not measured
*Therisk in the intervention group (and its 95% confidence interval) is based on the assumed risk in the comparison group and the relative effect of the intervention (and its 95% CI).
CI: confidence interval; NEECHAM: Neelon and Champagne; RR: risk ratio.
GRADE Working Group grades of evidence
 High certainty: further research is very unlikely to change our confidence in the estimate of effect.
 Moderate certainty: further research is likely to have an important impact on our confidence in the estimate of effect and may change the estimate.
 Low certainty: further research is very likely to have an important impact on our confidence in the estimate of effect and is likely to change the estimate.
 Very low certainty: we are very uncertain about the estimate.

aAssessed at high risk of methodological bias for blinding, outcome data and other bias.
 bOne trial only so not possible to assess for consistency.
 cVery low rate of delirium events. Wide confidence limits indicate uncertainty; downgraded two levels for imprecision.