Skip to main content
. 2017 Apr 12;2017(4):CD001431. doi: 10.1002/14651858.CD001431.pub5

Thomson 2007.

Methods Randomized to decision aid vs usual care by clinical guidelines
Participants 69 + 67 patients with atrial fibrillation considering treatment options in the UK
Interventions DA (in consultation): computerized decision on options' outcomes, clinical problem, outcome probabilities, explicit values clarification, guidance/coaching by physician
Comparator: guidelines applied as direct advice
Outcomes Primary outcome: decisional conflict
Secondary outcomes: anxiety, knowledge, resource use, choice, health outcomes (stroke, transient ischaemic attack, bleeding events)
Notes
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Low risk "[E]lectronically‐generated random permuted blocks via a web‐based randomisation service" (p 2, Recruitment and randomization)
Allocation concealment (selection bias) Low risk "[E]lectronically‐generated random permuted blocks via a web‐based randomisation service" (p 2, Recruitment and randomization)
Blinding of participants and personnel (performance bias) 
 All outcomes Unclear risk Physicians were blinded. Unclear if patients are blinded and how that may affect the outcome
Blinding of outcome assessment (detection bias) 
 All outcomes Low risk Unclear blinding but outcomes were objectively measured and not subjective to interpretation
Incomplete outcome data (attrition bias) 
 All outcomes Low risk See flow diagram
Selective reporting (reporting bias) Low risk ISRCTN24808514
Other bias Low risk Baseline characteristics similar, sample size similar, not stopped early