Date	Event	Description
25 June 2012	New citation required and conclusions have changed	An update search was performed for this review on 15 July 2011 and 25 June 2012. One additional study was included (Lloret 2009); the results and conclusions have changed. The authors of the review have changed.
15 July 2011	New search has been performed	An update search was performed for this review on 15 July 2011.
18 March 2009	New search has been performed	Update search of 5 March 2009 retrieved new studies for consideration for inclusion
25 April 2008	New citation required but conclusions have not changed	In 2007, the scope of this review was broadened to include both Alzheimer's disease patients and patients with mild cognitive impairment
16 January 2007	New search has been performed	Update 2007: one new study was included (Petersen 2005). The included study did not affect the results as it also showed that vitamin E has no more significant effect than placebo for mild cognitive impairment. The overall conclusion of the review has not changed as there is not enough evidence to support the use of vitamin E in the treatment of Alzheimer's disease or mild cognitive impairment.
2 November 2006	New citation required and conclusions have changed	Substantive amendment