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. 2017 Apr 9;2017(4):CD004022. doi: 10.1002/14651858.CD004022.pub4

1132 Ishimitsu 1996 A.

Methods Op
 CO
Participants N HT: 23 (M/F:11/12) NT 7 (M/F:3/4)(B/W/A.0/0/30)
 Hypertension and normotension
 Age 54
Interventions SR 194 (217‐23)
 Dur 7
Outcomes SBP, DBP, renin, aldo
Notes LoFo: 0
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Insufficient information
Allocation concealment (selection bias) Unclear risk Insufficient information
Blinding (performance bias and detection bias) 
 All outcomes High risk Open study
Incomplete outcome data (attrition bias) 
 All outcomes Low risk Lost to follow up 0
Selective reporting (reporting bias) Low risk No distinct selective outcome reporting
Blinding of participants and personnel (performance bias) 
 All outcomes High risk Open study: Performance bias due to knowledge of the allocated interventions by participants and personnel during the study.
Blinding of outcome assessment (detection bias) 
 All outcomes High risk Open study: Detection bias due to knowledge of the allocated interventions by outcome assessors