1144 Foo 1998.

Methods	DB CO
Participants	N 18, (8 males, 10 females) Normotensive Mean age 51
Interventions	SR 149 (227‐78) Dur 6
Outcomes	SBP DBP Renin Aldosterone
Notes	LoFo: 0 SDs estimated on the basis of p‐values
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	Insufficient information
Allocation concealment (selection bias)	Unclear risk	Insufficient information
Blinding (performance bias and detection bias) All outcomes	Low risk	Double blind study
Incomplete outcome data (attrition bias) All outcomes	Low risk	Lost to follow‐up 0
Selective reporting (reporting bias)	Low risk	No distinct selective outcome reporting
Blinding of participants and personnel (performance bias) All outcomes	Low risk	Double blind study
Blinding of outcome assessment (detection bias) All outcomes	Low risk	Double blind study