Methods |
Op
CO |
Participants |
N 42 (M/F:34/8)(B/W/A.0/42/0)
Normotension
Age 26 |
Interventions |
SR 237 (273‐36)
Dur 4 |
Outcomes |
SBP, DBP, renin, aldo, NE, E, chol, HDL, LDL, Trig |
Notes |
LoFo: 0 |
Risk of bias |
Bias |
Authors' judgement |
Support for judgement |
Random sequence generation (selection bias) |
Unclear risk |
Insufficient information |
Allocation concealment (selection bias) |
Unclear risk |
Insufficient information |
Blinding (performance bias and detection bias)
All outcomes |
High risk |
Open study |
Incomplete outcome data (attrition bias)
All outcomes |
Low risk |
Lost to follow‐up 0 |
Selective reporting (reporting bias) |
Low risk |
No distinct selective outcome reporting |
Blinding of participants and personnel (performance bias)
All outcomes |
High risk |
Open study: Performance bias due to knowledge of the allocated interventions by participants and personnel during the study. |
Blinding of outcome assessment (detection bias)
All outcomes |
High risk |
Open study: Detection bias due to knowledge of the allocated interventions by outcome assessors |