| Methods |
Op
CO |
| Participants |
N 14 (M/F:14/0)(B/W/A.0/14/0)
Norm
Age 57 |
| Interventions |
SR 129 (188‐59)
Dur 7 |
| Outcomes |
SBP
DBP
NE and E |
| Notes |
LoFo: 2 excluded because of side effects |
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Random sequence generation (selection bias) |
Unclear risk |
Insufficient information |
| Allocation concealment (selection bias) |
Unclear risk |
Insufficient information |
| Blinding (performance bias and detection bias)
All outcomes |
High risk |
Open study |
| Incomplete outcome data (attrition bias)
All outcomes |
Low risk |
Lost to follow up 2/14 |
| Selective reporting (reporting bias) |
Low risk |
No distinct selective outcome reporting |
| Blinding of participants and personnel (performance bias)
All outcomes |
High risk |
Open study: Performance bias due to knowledge of the allocated interventions by participants and personnel during the study. |
| Blinding of outcome assessment (detection bias)
All outcomes |
High risk |
Open study: Detection bias due to knowledge of the allocated interventions by outcome assessors |
