1192 Townsend 2007.

Methods	Op CO
Participants	N 20 (M/F:12/8)(B/W/A.10/9/1) Norm Age 30
Interventions	SR 171 (194‐23) Dur 6
Outcomes	SBP DBP Aldo Renin
Notes	Randomized 21. LoFo: 3 IT: No
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Low risk	Prespecified randomised blocked table
Allocation concealment (selection bias)	Unclear risk	Insufficient information
Blinding (performance bias and detection bias) All outcomes	High risk	Open study
Incomplete outcome data (attrition bias) All outcomes	Low risk	Lost to follow up 3/21
Selective reporting (reporting bias)	Low risk	No distinct selective outcome reporting
Blinding of participants and personnel (performance bias) All outcomes	High risk	Open study: Performance bias due to knowledge of the allocated interventions by participants and personnel during the study.
Blinding of outcome assessment (detection bias) All outcomes	High risk	Open study: Detection bias due to knowledge of the allocated interventions by outcome assessors