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. 2017 Apr 9;2017(4):CD004022. doi: 10.1002/14651858.CD004022.pub4

1208 Todd 2012.

Methods SB, Co
Participants N 23 (M/F:5/18)(B/W/A.0/23/0)
Normotension
Age 43.7
Interventions SR 140
Dur 28
Outcomes SBP, DBP
Notes 28 screened, 25 included, 23 randomized. LoFo. 4
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Low risk Randomization was carried out by a third party using http:// www.randomization.com to generate the randomization
 sequence for the tomato juice interventions.
Allocation concealment (selection bias) Low risk The sequence was given to the Dunedin hospital pharmacy, where a study dedicated
 pharmacist added the allocated amount of salt to the tomato juice.
Blinding (performance bias and detection bias) 
 All outcomes Low risk Single blind study
Incomplete outcome data (attrition bias) 
 All outcomes Low risk Lost to follow up 4/23
Selective reporting (reporting bias) Unclear risk No distinct selective reporting
Blinding of participants and personnel (performance bias) 
 All outcomes Low risk The investigators remained blind to the randomization sequence throughout the study. Participants were initially blind to the randomization sequence, but once they began each phase of the intervention they were aware of the presence or absence of added salt. They were asked not to tell the investigator which tomato juice they had received.
Blinding of outcome assessment (detection bias) 
 All outcomes Low risk Outcome detection blinded