| Methods |
Op
CO |
| Participants |
N10
Norm
Age46 |
| Interventions |
SR341
Dur4 |
| Outcomes |
SBP
DBP
Aldo
Renin |
| Notes |
LoFo: 0 |
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Random sequence generation (selection bias) |
Unclear risk |
Insufficient information |
| Allocation concealment (selection bias) |
Unclear risk |
Insufficient information |
| Blinding (performance bias and detection bias)
All outcomes |
High risk |
Open study |
| Incomplete outcome data (attrition bias)
All outcomes |
Low risk |
Lost to follow up 0 |
| Selective reporting (reporting bias) |
Low risk |
No distinct selective outcome reporting |
| Blinding of participants and personnel (performance bias)
All outcomes |
High risk |
Open study: Performance bias due to knowledge of the allocated interventions by participants and personnel during the study. |
| Blinding of outcome assessment (detection bias)
All outcomes |
High risk |
Open study: Detection bias due to knowledge of the allocated interventions by outcome assessors |
