Methods | 36‐month randomised comparative trial Parallel study design Study conducted in Poland Method of generation of random list and allocation concealment not stated |
|
Participants | Adults with newly diagnosed epilepsy Number randomised: PHT = 30; SV = 30 100% partial epilepsy, age range: 18 to 40 years Percentage men and range of follow‐up not mentioned |
|
Interventions | Monotherapy with PHT or SV Starting doses: PHT: 200 mg/day, SV: 600 mg/day. Dose achieved not stated |
|
Outcomes | Proportion achieving 24‐month remission at 3 years Exclusions after randomisation due to adverse events or no efficacy | |
Notes | Abstract only. Outcomes chosen for this review were not reported. IPD pledged but not received | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | Trial "randomised" but no further information provided |
Allocation concealment (selection bias) | Unclear risk | No information provided |
Blinding of participants and personnel (performance bias) All outcomes | Unclear risk | No information provided |
Blinding of outcome assessment (detection bias) All outcomes | Unclear risk | No information provided |
Incomplete outcome data (attrition bias) All outcomes | Unclear risk | "Exclusion rates" (interpreted as withdrawal rates) reported for all treatment groups, no further information provided |
Selective reporting (reporting bias) | Unclear risk | No protocol available and trial reported only in abstract form, outcomes for this review not available |
Other bias | Unclear risk | Insufficient detail provided in abstract to allow judgement |