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. 2019 Apr 23;25:222–236.

Table 2. Significant enriched genes pathways.

Pathway Name N FDR p value Genes in the pathway
TCA Cycle 7 0.0002 Pdk1 Fh1 Pdk4 Idh2 Pdk2 Sdhd Dld
MAPK signaling pathway 12 0.0031 Dusp6 Dusp10 Stmn1 Ppp5c Dusp4 Mapk6 Akt3 Map4k4 Hspa1a Map3k12 Dusp1 Map3k5
Focal Adhesion 12 0.0037 Ppp1r12a Vegfc Tnxb Rhob Pak7 Araf Mapk6 Pak4 Flt1 Akt3 Vegfb Itga9
One carbon metabolism and related pathways 6 0.0037 Gclc Cth Gsr Gss Chka Gnmt
Glycolysis and Gluconeogenesis 6 0.0037 Tpi1 Pfkm Pfkp Slc2a3 Dld Hk1
Amino Acid metabolism 9 0.0041 Fh1 Bcat1 Cth Gss Sdhd Glud1 Pdk4 Gsr Dld
Myometrial Relaxation and Contraction Pathways 9 0.0209 Rgs10 Ywhaz Rgs5 Camk2g Cald1 Rgs2 Prkd1 Igfbp2 Prkar1a
Glutathione and one carbon metabolism 4 0.0214 Gclc Cth Gsr Gss
Electron Transport Chain 6 0.0271 Slc25a4 Slc25a14 Atp5b Ndufs4 Atp5j Sdhd
Mitochondrial Gene Expression 3 0.0319 Pprc1 Tfam Nrf1
Chemokine signaling pathway 9 0.0319 Nfkbib Cxcl14 Cxcl16 Prkx Akt3 Adrbk1 Cx3cl1 Nfkbia Csk
Calcium Regulation in the Cardiac Cell 8 0.0319 Atp1b1 Rgs10 Ywhaz Rgs5 Camk2g Rgs2 Prkd1 Prkar1a
Glutathione metabolism 3 0.0319 Gclc Gsr Gss
Apoptosis 6 0.0403 Xiap Nfkbib Bcl2l2 Dffa Nfkbia Cycs
EGFR1 Signaling Pathway 10 0.0403 Pebp1 Ralbp1 Araf Ceacam1 Git1 Prkd1 Dusp1 Csk Tgif1 Prkar1a
Insulin Signaling 8 0.0408 Mapk11 Mapk6 Pfkm Map4k4 Trib3 Gys1 Map3k12 Map3k5
Regulation of Actin Cytoskeleton 8 0.0408 Ppp1r12a Pak7 Mapk6 Pak4 Limk1 Gsn Git1 Csk
Translation Factors 4 0.0408 Eif2b1 Eef1a2 Eif1a Eef2
Oxidative Stress 3 0.0408 Gclc Gsr Txn2
Integrin-mediated cell adhesion 6 0.041 Akt3 Araf Mapk6 Pak4 Csk Itga9
B Cell Receptor Signaling Pathway 9 0.041 Dusp6 Plekha1 Dusp4 Pdk2 Cd81 Hnrnpk Prkd1 Nfkbia Csk