Comparison 1.

Regimens containing macrolides (azithromycin) versus tetracycline (doxycycline)

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Effectiveness of cure in mild‐moderate PID	2	243	Risk Ratio (M‐H, Random, 95% CI)	1.18 [0.89, 1.55]
2 Sensitivity analysis by risk of bias: effectiveness of cure in mild‐moderate PID	1	133	Risk Ratio (M‐H, Fixed, 95% CI)	1.35 [1.10, 1.67]
3 Effectiveness of cure in severe PID	1	309	Risk Ratio (M‐H, Fixed, 95% CI)	1.00 [0.96, 1.05]
4 Any antibiotic‐related adverse effect leading to discontinuation use of macrolide versus tetracycline	3	552	Risk Ratio (M‐H, Fixed, 95% CI)	0.71 [0.38, 1.34]