Roy 1985

Methods	Randomized controlled trial.
Participants	Inclusion criteria: not stated. Exclusion criteria: not stated. Number of women randomized: 46 (36 with acute PID). Number of women analyzed: group A: 19; group B: 9; group C: 9. Number of withdrawals/exclusions/loss to follow‐up and reasons: all 46 women completed the study; however, only 36 had acute PID. Number of centres: 1. Age (years): not stated. Country: US.
Interventions	Group A: cefotaxime 2 g IV or IM every 8 h. Group B: clindamycin 600 mg IV every 6 h + gentamicin 1.5 mg/kg lean bodyweight IV or IM every 8 h. Group C: clindamycin 600 mg IV every 6 h + gentamicin 1.5 mg/kg lean bodyweight IV or IM every 8 h + penicillin G 5 million units IM every 4 h.
Outcomes	Primary outcomes: clinical cure: antibiotic change was made for treatment failure from an assigned regimen based upon persistence or worsening of signs and symptoms after 48 h. Secondary outcomes: none reported.
Notes	Ethical approval: not stated. Informed consent: yes, enrolled after informed consent obtained. Source of funding: not stated, and no conflicts of interest reported. Range of hospital stay: 3‐11 days.
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	Not stated.
Allocation concealment (selection bias)	Unclear risk	Not stated.
Blinding of participants and personnel (performance bias) All outcomes	Unclear risk	Not stated.
Blinding of outcome assessment (detection bias) All outcomes	Unclear risk	Not stated.
Incomplete outcome data (attrition bias) All outcomes	Low risk	All women randomized completed the study.
Selective reporting (reporting bias)	Unclear risk	No study protocol found.
Other bias	Unclear risk	Not stated.