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. 2019 Apr 23;14(4):e0215997. doi: 10.1371/journal.pone.0215997

Table 4. Decision statistics for the change of VE/VCO2 and PETCO2 cut-off values and HVS.

VE/VCO2 ratio            
Δ (peak-rest) sensitivity specificity +LR -LR PPV NPV
+5 31 (15–51) 97 (82–100) 9 (1.2–67) 0.7 (0.6–0.9) 90 (55–99) 58 (52–64)
0 52 (33–71) 83 (64–94) 3 (1.3–7.2) 0.6 (0.4–0.9) 75 (56–88) 63 (53–72)
-5 83 (64–94) 59 (39–76) 2 (1.3–3.2) 0.3 (0.1–0.7) 67 (56–76) 77 (59–89)
-10 97 (82–100) 34 (18–54) 1.5 (1.1–1.9) 0.1 (0.01–0.73) 60 (53–66) 91 (58–99)
PETCO2 (mmHg)
Δ (peak-rest) sensitivity specificity +LR -LR PPV NPV
-5 21 (8–40) 100 (88–100) - 0.8 (0.7–1) 100 56 (51–60)
0 55 (36–74) 93 (77–99) 8 (2–31) 0.5 (0.3–0.7) 89 (67–97) 68 (58–76)
+5 83 (64–94) 62 (42–79) 2.2 (1.3–3.6) 0.3 (0.1–0.7) 69 (57–78) 78 (61–89)
+10 93 (77–99) 14 (4–32) 1.1 (0.9–1.3) 0.5 (0.1–2.5) 52 (48–56) 67 (28–91)

Δ = delta; +LR = positive likelihood ratio; -LR = negative likelihood ratio; NPV = negative predictive value; PETCO2 = partial pressure of end-tidal carbon dioxide; PPV = positive predictive value; VE/VCO2 = ventilatory efficiency