Table.
Patient Details
| Patient* | PWS | Sex (Race) | Age (yr) | Body Mass Index, kg/m2 (% Body Fat) | Pitolisant Dosage (mg/day) | |
|---|---|---|---|---|---|---|
| Before Pitolisant | After Pitolisant | |||||
| A | Deletion | Male (Caucasian) | 12 | 16.4 (18.5) | 15.2 (19.5) | 4.5–27 |
| B | Uniparental disomy | Female (Caucasian) | 10 | 20 (30.2) | 22.5 (31.4) | 4.5–27 |
| C† | Deletion | Female (Caucasian) | 15 | 23.1 (not available) | 23.6 (not available) | 4.5–31.5 |
*All children received nightly growth hormone injections.
† At initiation of treatment with pitolisant, Patient C also received escitalopram, buspirone, risperidone, levoxythyroxine, and estradiol.