Figure 6. The distribution of AF episodes in 3-hour bins over a 24-hour period of all patients studied.

(A) The number of AF onset. There were a peak in early morning and another one prior to midnight. Among them, only the early morning peak had significantly (*P < 0.00179) more episodes than other times of the day adjusted by Bonferroni correction. (B) Similar to A, the distribution of IRAF episodes shows a significant peak in early morning. (C) There was no significant difference in the distribution of non-IRAF episodes at different times of the day. P values in A–C were determined by the χ² goodness-of-fit test, and post hoc pair-wise comparison of the number of AF onset were performed by the exact binomial test with Bonferroni correction. AF, atrial fibrillation.