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. Author manuscript; available in PMC: 2020 May 1.
Published in final edited form as: J Invest Dermatol. 2018 Nov 20;139(5):1082–1088. doi: 10.1016/j.jid.2018.10.040

Figure 3. The effect of dietary pyrophosphate (PPi) on the chronic (PXE-like) calcification phenotype of Abcc6−/− mice.

Figure 3

A: Vibrissae calcification from Abcc6−/− mice fed either low (5053) or high (2920) PPi chow was quantified. The data was collected from 6- and 12-months old animals when whiskers calcification is optimal. Results pre- and post-dating the change of institutional rodent chow in 2015 were compiled to generate these results. The number of mice per group is shown and results are +/− SEM. **** p<0.0001. B: Representative images of vibrissae calcification (chronic PXE-like phenotype) of Abcc6−/− mice visualized by Alizarin Red S staining (red to dark red color) are shown. Scale bar: 250μm.