Table 2.
Predicted GFR values, slopes and paired differences between predicted and observed GFR at different ages using polynomial model
| Age (yr) | 20-30 | 30-40 | 40-50 | 50-60 | |
|---|---|---|---|---|---|
| Class A | GFR | 109 (95-123) | 110 (99-121) | 97 (83-110) | 69 (49-90) |
| Slope | 0.77 | −0.63 | −2.03 | −3.42 | |
| Diff (SE) | −2.19 (5.56) | −2.27 (11.00) | −4.84 (5.26) | 12.19 (2.33) | |
| Class B | GFR | 113 (106-120) | 108 (103-113) | 89 (82-96) | 56 (45-67) |
| Slope | 0.21 | −1.19 | −2.58 | −3.98 | |
| Diff (SE) | 6.51 (5.96) | 5.77 (3.55) | 5.83 (3.88) | −0.06 (7.24) | |
| Class C | GFR | 113 (107-119) | 101 (96-106) | 75 (68-82) | 35 (24-45) |
| Slope | −0.52 | −1.92 | −3.32 | −4.71 | |
| Diff (SE) | 2.39 (5.38) | 9.27 (3.98) | 8.84 (3.77) | 6.42 (5.19) | |
| Class D | GFR | 119 (112-125) | 92 (87-98) | 51 (44-59) | −3.23 (−15.73-9.26) |
| Slope | −1.97 | −3.37 | −4.77 | −6.16 | |
| Diff (SE) | 4.40 (5.71) | 7.00 (4.25) | 6.34 (5.26) | 21.13 (5.59) | |
| Class E | GFR | 103 (97-110) | 64 (57-71) | 10 (0-21) | 0 |
| Slope | −3.25 | −4.65 | −6.05 | ||
| Diff (SE) | −0.93 (4.94) | 1.99 (5.65) | 20.27 (6.92) | ||
Units of GFR are mL/min/1.73 m2 (95% CI); slopes are mL/min/1.73 m2 per year
Diff (SE) are calculated based on the midpoint of age intervals.
Diff = observed GFR - predicted GFR; positive means underestimated