Table 1.

A 2-way ANOVA of each measured variable as a function of condition (ME/CFS vs healthy control), timepoint, and interactions. Variables with at least one significant effect were constrained; others were left free.

Variable	Condition	Time	Condition × Time	Constrained (Y/N)
IL-lα	0.413	0.171	0.643	N
IL-1β	0.017	0.173	0.722	Y
IL-2	<0.001	0.523	0.899	Y
IL-4	<0.001	0.585	0.550	Y
IL-5	0.002	0.088	0.293	Y
IL-6	<0.001	0.433	0.035	Y
IL-8	0.481	0.760	0.869	N
IL-10	0.673	0.984	0.231	N
IL-12	0.825	0.588	0.580	N
IL-13	<0.001	0.403	0.009	Y
IL-15	0.041	0.337	0.343	Y
IL-17	0.257	0.802	0.627	N
IL-23	0.462	0.963	0.991	N
IFNγ	0.298	0.918	0.967	N
TNFα	0.584	0.244	0.894	N
B cell	0.672	0.369	0.991	N
NK cell	<0.001	<0.001	0.285	Y