. Author manuscript; available in PMC: 2020 May 1.

Published in final edited form as: J Immunol. 2019 Mar 25;202(9):2760–2771. doi: 10.4049/jimmunol.1900039

Table 1. Tissue inflammation, injury and lung mechanics.

Summary analysis for BALF protein content, BALF cell counts and in vivo pulmonary function testing (inspiratory capacity, static compliance and tissue damping) from control (tamoxifen treated SP-C^WT/WTFlp^+/+ or oil treated SP-C^I73T/I73TFlp^+/− mice) and tamoxifen treated (250 mg/kg;i.p.) SP-C^I73T/I73TFlp^+/− mice at 3 d, 7 d and 2 wk. Note that control data represents pooled data from 3 d (N=3), 7 d (N=4), and 2 wk (N=4). Data is represented as mean ± SEM.

Table 1		Protein Content (µg/ml)	Cell Count (10⁶)	Inspiratory Capacity (ml)	Static Compliance (ml/cm_H2O)	Tissue Damping (G, cmH₂O/ml)
	CTL (N=11)	438.2 ± 38.3	0.26 ± 0.02	0.74 ± 0.02	0.067 ± 0.002	4.59 ± 0.15
SP-C^I73T/I73TFlp^+/−	3 d (N=8)	455.9 ± 61.6	0.19 ± 0.03	0.66 ± 0.03	0.057 ± 0.003	5.11 ± 0.28
	7 d (N=7)	2266.6 ± 422.5^*	0.99 ± 0.18^*	0.51 ± 0.05^*	0.040 ± 0.005^*	7.62 ± 0.74^*
	2 wk (N=14)	2245.2 ± 245.0^*	2.66 ± 0.32^*	0.46 ± 0.03^*	0.031 ± 0.004^*	8.84 ± 1.35^*

p < 0.05 compared to control SP-C^WT/WTFlp^+/+ or oil treated SP-C^I73T/I73TFlp^+/− mice SP-C^I73T/I73TER^−/− by ANOVA, using Tukey post-hoc test.