Skip to main content
. 2018 Oct 23;3(4):e10084. doi: 10.1002/jbm4.10084

Figure 6.

Figure 6

Analyses of serum bone formation and resorption markers. Both wild‐type and Col2.3‐hWNT16 mice showed significantly lower levels of serum P1NP at 2 weeks after pellet implantation due to GC treatment compared with genotype‐matched placebo‐treated mice. Serum levels of CTX and TRAP were similar in GC‐treated wild‐type mice compared with placebo‐treated mice in both male (A) and female (B) mice at 28 days after pellet implantation. A slightly higher but nonsignificant level of CTX and TRAP were observed in GC‐treated Col2.3‐hWNT16 mice compared with placebo group in both sexes. Values are given as mean ± SEM; *p < 0.05, **p < 0.005, and ***p < 0.0001versus genotype‐matched placebo‐treated mice using Student's t test. GC = glucocorticoid.