Table 2.
Potential predictors at term age of neurodevelopment delay assessed at 24 months of corrected age among VLBW infants from a prospective multicenter cohort study, 2012–2014
| Potential predictors | Result | Neurodevelopmental delay, n/N (cumulative incidencea) | Relative risk (95% CI) | |
|---|---|---|---|---|
| Crude | Adjustedb | |||
| Abnormal neurological examination | No | 11/63 (17.5) | ||
| Yes | 24/69 (34.8) | 2.0 (1.1–3.7) | ||
| Microcephaly | No | 23/117 (19.7) | ||
| Yes | 12/15 (80.0) | 4.1 (2.6–6.4) | 3.2 (1.6–6.7) | |
| Major brain abnormality | No | 24/117 (20.5) | ||
| Yes | 11/15 (73.3) | 3.6 (2.2–5.7) | 2.7 (1.3–5.7) | |
Cases/100 infants/2 years.
Calculated from a multivariable Poisson linear model in which the three potential predictors entered but then abnormal neurological examination was excluded because of lack of association