Table 1.
Non-alcoholic fatty liver disease-Kyoto Encyclopedia of Genes and Genomes pathway (hsa04932)
| Gene symbol; description |
| IL6; interleukin 6 |
| IL6R; interleukin 6 receptor |
| SOCS3; suppressor of cytokine signaling 3 |
| TNF; tumor necrosis factor |
| TNFRSF1A; TNF receptor superfamily member 1A |
| NFKB1; nuclear factor kappa B subunit 1 |
| RELA; RELA proto-oncogene, NF-kB subunit |
| INS; insulin |
| INSR; insulin receptor |
| IRS1; insulin receptor substrate 1 |
| IRS2; insulin receptor substrate 2 |
| PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha |
| PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta |
| PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta |
| PIK3R1; phosphoinositide-3-kinase regulatory subunit 1 |
| PIK3R2; phosphoinositide-3-kinase regulatory subunit 2 |
| PIK3R3; phosphoinositide-3-kinase regulatory subunit 3 |
| AKT1; AKT serine/threonine kinase 1 |
| AKT2; AKT serine/threonine kinase 2 |
| AKT3; AKT serine/threonine kinase 3 |
| GSK3A; glycogen synthase kinase 3 alpha |
| GSK3B; glycogen synthase kinase 3 beta |
| NR1H3; nuclear receptor subfamily 1 group H member 3 |
| RXRA; retinoid X receptor alpha |
| SREBF1; sterol regulatory element binding transcription factor 1 |
| MLX; MLX, MAX dimerization protein |
| MLXIP; MLX interacting protein |
| MLXIPL; MLX interacting protein like |
| PKLR; pyruvate kinase L/R |
| LEP; leptin |
| LEPR; leptin receptor |
| ADIPOQ; adiponectin, C1Q and collagen domain containing |
| ADIPOR1; adiponectin receptor 1 |
| ADIPOR2; adiponectin receptor 2 |
| PRKAA1; protein kinase AMP-activated catalytic subunit alpha 1 |
| PRKAA2; protein kinase AMP-activated catalytic subunit alpha 2 |
| PRKAB1; protein kinase AMP-activated non-catalytic subunit beta 1 |
| PRKAB2; protein kinase AMP-activated non-catalytic subunit beta 2 |
| PRKAG1; protein kinase AMP-activated non-catalytic subunit gamma 1 |
| PRKAG3; protein kinase AMP-activated non-catalytic subunit gamma 3 |
| PRKAG2; protein kinase AMP-activated non-catalytic subunit gamma 2 |
| PPARA; peroxisome proliferator activated receptor alpha |
| CDC42; cell division cycle 42 |
| RAC1; Rac family small GTPase 1 |
| MAP3K11; mitogen-activated protein kinase kinase kinase 11 |
| MAPK8; mitogen-activated protein kinase 8 |
| MAPK10; mitogen-activated protein kinase 10 |
| MAPK9; mitogen-activated protein kinase 9 |
| ITCH; itchy E3 ubiquitin protein ligase |
| ERN1; endoplasmic reticulum to nucleus signaling 1 |
| TRAF2; TNF receptor associated factor 2 |
| MAP3K5; mitogen-activated protein kinase kinase kinase 5 |
| JUN; Jun proto-oncogene, AP-1 transcription factor subunit |
| IL1A; interleukin 1 alpha |
| IL1B; interleukin 1 beta |
| IKBKB; inhibitor of nuclear factor kappa B kinase subunit beta |
| XBP1; X-box binding protein 1 |
| CEBPA; CCAAT enhancer binding protein alpha |
| CYP2E1; cytochrome P450 family 2 subfamily E member 1 |
| FASLG; Fas ligand |
| CXCL8; C-X-C motif chemokine ligand 8 |
| TGFB1; transforming growth factor beta 1 |
| EIF2AK3; eukaryotic translation initiation factor 2 alpha kinase 3 |
| EIF2S1; eukaryotic translation initiation factor 2 subunit alpha |
| ATF4; activating transcription factor 4 |
| DDIT3; DNA damage inducible transcript 3 |
| BCL2L11; BCL2 like 11 |
| BAX; BCL2 associated X, apoptosis regulator |
| FAS; Fas cell surface death receptor |
| CASP8; caspase 8 |
| BID; BH3 interacting domain death agonist |
| CYCS; cytochrome c, somatic |
| CASP3; caspase 3 |
| CASP7; caspase 7 |
| NDUFV1-3; NADH:ubiquinone oxidoreductase core subunit V1 –V3 |
| NDUFA1-3; NADH:ubiquinone oxidoreductase subunit A1-3 |
| NDUFA4; NDUFA4, mitochondrial complex associated |
| NDUFA4L2; NDUFA4, mitochondrial complex associated like 2 |
| NDUFA5-13; NADH:ubiquinone oxidoreductase subunit A5-A13 |
| NDUFAB1; NADH:ubiquinone oxidoreductase subunit AB1 |
| NDUFB1-11; NADH:ubiquinone oxidoreductase subunit B1-B11 |
| NDUFS1-S8; NADH:ubiquinone oxidoreductase core subunit S1 –S8 |
| NDUFC1; NADH:ubiquinone oxidoreductase subunit C1 |
| NDUFC2; NADH:ubiquinone oxidoreductase subunit C2 |
| NDUFC2-KCTD14; NDUFC2-KCTD14 readthrough |
| SDHA; succinate dehydrogenase complex flavoprotein subunit A |
| SDHB; succinate dehydrogenase complex iron sulfur subunit B |
| SDHC; succinate dehydrogenase complex subunit C |
| SDHD; succinate dehydrogenase complex subunit D |
| UQCRFS1; ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 |
| CYTB; cytochrome b |
| CYC1; cytochrome c1 |
| UQCRC1; ubiquinol-cytochrome c reductase core protein 1 |
| UQCRC2; ubiquinol-cytochrome c reductase core protein 2 |
| UQCRH; ubiquinol-cytochrome c reductase hinge protein |
| UQCRHL; ubiquinol-cytochrome c reductase hinge protein like |
| UQCRB; ubiquinol-cytochrome c reductase binding protein |
| UQCRQ; ubiquinol-cytochrome c reductase complex III subunit VII |
| UQCR10; ubiquinol-cytochrome c reductase, complex III subunit X |
| UQCR11; ubiquinol-cytochrome c reductase, complex III subunit XI |
| COX3; cytochrome c oxidase III |
| COX1; cytochrome c oxidase subunit I |
| COX2; cytochrome c oxidase subunit II |
| COX4I2; cytochrome c oxidase subunit 4I2 |
| COX4I1; cytochrome c oxidase subunit 4I1 |
| COX5A; cytochrome c oxidase subunit 5A |
| COX5B; cytochrome c oxidase subunit 5B |
| COX6A1; cytochrome c oxidase subunit 6A1 |
| COX6A2; cytochrome c oxidase subunit 6A2 |
| COX6B1; cytochrome c oxidase subunit 6B1 |
| COX6B2; cytochrome c oxidase subunit 6B2 |
| COX6C; cytochrome c oxidase subunit 6C |
| COX7A1; cytochrome c oxidase subunit 7A1 |
| COX7A2; cytochrome c oxidase subunit 7A2 |
| COX7A2L; cytochrome c oxidase subunit 7A2 like |
| COX7B; cytochrome c oxidase subunit 7B |
| COX7B2; cytochrome c oxidase subunit 7B2 |
| COX7C; cytochrome c oxidase subunit 7C |
| COX8C; cytochrome c oxidase subunit 8C |
| COX8A; cytochrome c oxidase subunit 8A |
https://www.genome.jp/kegg-bin/show_pathway? hsa04932.