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. 2019 Apr 17;13:359. doi: 10.3389/fnins.2019.00359

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Copyright © 2019 Zenz, Jačan, Reichmann, Farzi and Holzer.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Experimental time lines and body weight recordings. (A) Time course of the effects of i.p. injection of vehicle or Poly(I:C) (12 mg/kg) on locomotor and exploratory behavior as well as food and water intake assessed in the LabMaster system (n = 6). (B) Effect of intermittent fasting (IF) for 9 days on the sickness behavior in the open field (OF) evoked by i.p. injection of vehicle or Poly(I:C) (12 mg/kg) on day 10 (n = 7–9). (C) Body weight of mice at days 0 and 10 (n = 6). RM two-way ANOVA results: F(1, 10) = 0.7946, p = 0.3937 for interaction of time/feeding in body weight; F(1, 10) = 25.84, p ≤ 0.001 for main effect of time on body weight; F(1, 10) = 3.199, p = 0.1040 for main effect of feeding regimen on body weight. Abbreviations: AL, ad libitum feeding.