Table 1.
LC50/LD50 values of C. elegans strains after either 24 hours phosphine fumigation, UV and gamma irradiation.
| Treatment | Strain† | LD50/LC50‡ | R | Slope ± SE | X 2 | df |
|---|---|---|---|---|---|---|
| PH3 (ppm) | N2 | 301.88 (270.44–337.06) | 0.98 | 2.89 ± 0.19 | 6.03 | 6 |
| dld-1(wr4) | 1282.19 (739.32–2142.90)**** | 0.97 | 3.21 ± 0.23 | 19.36 | 5 | |
| SP483 | 164.02 (92.54–265.55)* | 0.99 | 1.99 ± 0.16 | 19.86 | 6 | |
| SP488 | 173.53 (153.05–195.56)* | 0.99 | 2.39 ± 0.15 | 6.47 | 6 | |
| DW102 | 225.20 (203.24–249.44)* | 0.99 | 3.32 ± 0.23 | 4.56 | 6 | |
| DW103 | 260.41 (233.42–290.44) | 0.98 | 2.93 ± 0.19 | 9.32 | 6 | |
| CE1255 | 238.67 (215.21–264.15)* | 0.99 | 3.06 ± 0.18 | 2.81 | 6 | |
| UV (J cm−2) | N2 | 18.35 (13.40–22.34) | 0.97 | 2.47 ± 0.20 | 12.95 | 7 |
| dld-1(wr4) | 31.07 (25.48–36.54)**** | 0.97 | 2.84 ± 0.19 | 16.81 | 8 | |
| SP483 | 15.06 (13.54–16.74) | 0.98 | 1.96 ± 0.11 | 13.86 | 10 | |
| SP488 | 13.84 (12.67–15.13) | 0.99 | 2.68 ± 0.15 | 11.97 | 9 | |
| CE1255 | 41.31 (35.43–47.79)**** | 0.97 | 4.18 ± 0.33 | 16.68 | 7 | |
| γ (Gy) | N2 | 401.23 (362.54–443.24) | 0.99 | 3.29 ± 0.21 | 3.61 | 7 |
| dld-1(wr4) | 654.58 (603.50–709.45)**** | 0.99 | 5.20 ± 0.44 | 0.72 | 4 | |
| DW102 | 333.67 (301.52–368.74) | 0.99 | 3.33 ± 0.21 | 1.62 | 7 | |
| DW103 | 344.28 (308.78–383.16) | 0.99 | 2.87 ± 0.17 | 5.77 | 7 | |
| CE1255 | 601.67 (551.33–654.74)**** | 0.99 | 4.44 ± 0.32 | 7.33 | 5 |
†N2 (wild type), dld-1(wr4) (phosphine-resistant), SP483 & SP488 (UV-sensitive), DW102 & DW103 (ionizing radiation-sensitive) and CE1255 (resistant to radiation-induced apoptosis).
‡*p < 0.05, ****p < 0.0001
Values were computed from probit analysis for each strain and treatment. One way ANOVA followed by Dunnett’s multiple comparison test was performed to identify significant differences in LC50 values due to exposure of each treatment between the wild type and the other strains.