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. 2019 Apr 23;9:6456. doi: 10.1038/s41598-018-38055-8

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Canonical analysis of principal coordinates (CAP) biplot constrained by time and treatment. The biplot was determined based on a Spearman’s correlation score of 0.4. Only bacterial taxa in the two opposing quadrants separating the CUS (chronic unpredictable stress) group pre- and post-treatment are indicated.