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. 2019 Apr 23;9:6466. doi: 10.1038/s41598-019-42923-2

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Cortico-cortical projection patterns along V1/V2 borders. (a) Optogenetic stimulation sites overlaid on the surface vessel pattern of the source area. Dashed line, the V1/V2 border. (b) Activation spots evoked by the stimulation of site 1–5 are overlaid on the vessel pattern of the target area. Color of the contours corresponds to the color of stimulation sites in (a). The individual spots are identified by capital alphabets. (c) Activation patterns and spots for individual stimulation sites. These results were obtained from M1. Please note that the activation of site 5 was electrophysiologically confirmed in Fig. 4. (d–f) Cortico-cortical projection patterns obtained from a different monkey (M4). Conventions are the same as in (a–c). Scale bars in (a) and (d–f), 1 mm. Scale bars in (b) and (c), 2 mm.